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Ongoing Projects

1. Immunohistochemistry study currently working on 14 different antibodies


2. Study on HPV prevalence and its significance in the prognosis of pre cancer and cancer of oral cavity- (N-200). (completed- 30% of work)


3. Early epigenetic changes contributing to the aggressiveness of oral cancer as well as to predict malignant transformation potential of potentially malignant disorders of oral cavity. (N-200) (completed 50% of sample collection)


4. Identification of diagnostic and prognostic markers in Oral squamous cell carcinoma and oral potentially malignant disorders. Development of low cost and rapid diagnostic kits for Oral squamous cell carcinoma and oral potentially malignant disorders. The molecular techniques used here are, exome sequencing, transcriptome sequencing, PCR, IHC and ELISA.


5. Repurposing of various drugs as adjunctive to Chemotherapy and Radiotherapy in Oral Squamous cell carcinoma. The preliminary work is on Oral cancer and normal oral epithelial cell lines.


6. Identifying various protein markers which can be used as diagnostic markers in low cost settings like places of mass screening, primary health centres etc. The technique used are two dimensional gel electrophoresis, IHC and ELISA.


7. Identification of secretory markers in Oral cancer and potential markers using Raman Spectroscopy (work is in very early phase).


8. Identification of diagnostic and prognostic markers in Oral Cancer and Oral Potentially Malignant Disorder using Spatial transcriptomics study (Applied for funding).


9. LIP PRINT PATTERNS IN PATIENTS WITH ORAL SQUAMOUS CELL CARCINOMA AND ORAL POTENTIALLY MALIGNANT DISORDERS


10. ANTIFUNGAL EFFICACY OF LACTOBACILLUS SPECIES AGAINST CANDIDA ISOLATED FROM ORAL SQUAMOUS CELL CARCINOMA PATIENTS – AN INVITRO STUDY


11. ECO-INSPIRED SYNTHESIS OF SELENIUM NANOPARTICLES USING ILLICIUM COCPAR PROJECT OUTLINE RECENT ON-GOING PROJECTS VERUM: UNVEILING ANTIOXIDANT, ANTIMICROBIAL,ANTI-CANCER,ANTI-INFLAMMATORY POTENTIALS.


12. The biogenic synthesis of copper nanoparticles using Cinnamomum tamala and its therapeutic action as anticancer, anti-inflammatory, antimicrobial, and antioxidant.


13. Cinnamomum verum mediated synthesis of copper nanoparticles and assessment of its anti- inflammatory, antioxidant, anticancer and antimicrobial potential.



S. No Ongoing Research Projects Year of Commencement Name of Staff / Student / Intern Total Cost (INR) Funding Agency
1 Oral Cancer Screening – Screening of patients and attendants reporting to OP 2013 Dr. Vidyarani Shyamsundar, Dr. S. Karthika Nagarajan 25,000 BIHER Funding
2 Re-purposing of Antihypertensive Drugs (Beta Blockers) and NSAIDs in OSCC – Preclinical studies 2018 Dr. Vidyarani Shyamsundar 18,50,000 DST-SERB
3 Important markers to assess prognosis of Oral Cancer and potentially malignant disorders 2014 Dr. Vidyarani Shyamsundar 3,50,000 BIHER Funding
4 Importance of EMT markers in Oral Cancer and potentially malignant disorders 2015 Dr. Vidyarani Shyamsundar 1,00,000 BIHER Funding
5 Single nucleotide polymorphism in OSCC and OPML 2016 Dr. Vidyarani Shyamsundar 4,00,000 BIHER Funding
6 Specific phytochemical as chemopreventive drug – Preliminary work 2017 Dr. Vidyarani Shyamsundar 1,00,000 BIHER Funding
7 Prevalence and virulence characterization of Candida in PMDs and OSCC 2015 Dr. Leena Sankari 25,000 BIHER Funding
8 Association of EBV in OSCC and potentially malignant disorders 2016 Dr. Leena Sankari, Dr. Kailash 20,000 BIHER Funding
9 Association of MMP-2 and MMP-9 in PMDs and OSCC using ELISA 2016 Dr. Vidyarani Shyamsundar, Dr. Sona 70,000 BIHER Funding
10 Assessment of HIV status among dental OP patients using ELISA 2017 Dr. Vidyarani Shyamsundar, Dr. Krishna Prasanth, Dr. Karthika Nagarajan 60,000 BIHER Funding
11 Phytochemical analysis of herbal extract for antioxidant & anti-inflammatory applications in PMDs 2017 Dr. S. Karthika Nagarajan 45,000 BIHER Funding
12 Expression of Anti-MRP8 in OSCC & OPMD 2019 Dr. Hariharan, Dr. Vidyarani Shyamsundar, Dr. KMK Masthan 40,000 BIHER Funding
13 Expression of Anti-Cystatin A in OSCC & OPMD 2019 Dr. Sangeethapriya P, Dr. Vidyarani Shyamsundar, Dr. KMK Masthan 40,000 BIHER Funding
14 Expression of Anti-Cystatin B in OSCC & OPMD 2019 Dr. Sudakshina Mukherjee, Dr. Vidyarani Shyamsundar, Dr. KMK Masthan 40,000 BIHER Funding
15 Expression of S-100A9 in OSCC & OPMD 2019 Dr. E. P. Sridevi Anjuga, Dr. Vidyarani Shyamsundar, Dr. KMK Masthan 40,000 BIHER Funding
16 Expression of S-100A11 in OSCC & OPMD 2019 Dr. Sherene A. M, Dr. Vidyarani Shyamsundar, Dr. KMK Masthan 40,000 BIHER Funding
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